Session:

Emerging Infectious Diseases

Abstract No.:

46.043

Title:

Carriage of Corynebacterium sp. among contacts diphtheria in a low resource area in Indonesia (interim report)

Author(s):

Y. Mulyastuti, D. Santosaningsih, A. Abdul Hamid, S. Santoso; Medical Faculty University of Brawijaya, Microbiology, Malang/ID

Abstract:

Background: In 2011, outbreak of diphtheria had occurred in East Java Province, Indonesia. Little is known about factors associated with the outbreak. Carriage of Corynebacterium diphtheria might play a role to the epidemiology of diphtheria. This study aimed to investigate the risk factors related to Corynebacterium diphtheria carriage among contacts diphtheria.
Methods: Screening of contacts diphtheria was conducted during February to November 2011 in 5 sub districts in Malang city, Indonesia. Throat swabs were taken from contacts diphtheria in 2 playgroups, 10 kindergartens, 10 elementary schools, 5 high schools, and 5 primary health cares. The swabs were inoculated to PAI culture medium and incubated at 37^oC overnight. Metachromatic staining (Neisser method) was carried out to the colony to identify Corynebacterium sp. Demographic data including gender, age, address, and screening location were collected.
Results: We screened 1739 contacts diphtheria in this study. 469/1739 (27%) were Corynebacterium sp positive. Logistic regression analysis showed that patients at the age of 19 and above and kindergarten screening location were associated with the carriage of Corynebacterium sp (p < 0.01 and p <0.05, respectively).
Conclusion: Contacts diphtheria in Malang city was at risk to be carriage of Corynebacterium sp.